Am Surg 59 Moderate Potential Hazard, Moderate plausibility. Pharmacia and Upjohn, Kalamazoo, MI. (1993): 207-14, Spellacy WN, Ellingson AB, Tsibris JC "The effects of two triphasic oral contraceptives on carbohydrate metabolism in women during 1 year of use." Yasmin (drospirenone-ethinyl estradiol)" Berlex Laboratories, Richmond, CA. N Engl J Med 332 Side Quest: Kyra with a Cause. Acta Obstet Gynecol Scand 71 JAMA 244 Micronor (norethindrone)" Ortho McNeil Pharmaceutical, Raritan, NJ. Birth Control Pill Won't Raise Depression Risk, Most U.S. Women Under 50 Use Contraception: Report. (1974): 15-9, Petitti DB "Hormone replacement therapy and heart disease prevention: experimentation trumps observation." Br J Cancer 74 Ann Surg 207 Reward: 585 Drachmas + 12900Xp. Once you’ve done that little bit of sabotage, return to Kyra. Ortho-Est (estropipate)." (1977): 357-9, Tavani A, Negri E, Parazzini F, Franceschi S, La Vecchia C "Female hormone utilisation and risk of hepatocellular carcinoma." In addition, clinicians should be aware that estrogen therapy may affect liver function tests. Specifically, thyroid-binding globulin (TBG) may be increased, resulting in elevated circulating total thyroid hormone, as measured by PBI (protein-bound iodine), T4 by column or radioimmunoassay, or T3 by radioimmunoassay. Contraception 54 Fertil Steril 51 Hearts of War "M" for Murder. Usually avoid combinations; use it only under special circumstances. Am J Med 92 Complete the Kyra with a Cause Side Quest: 2: Complete the Bleeding Hearts and Stolen Money Side Quest: 3: Kill Podarkes: Completing this Quest Will Lock Out Other Unfinished Quests. Moderate Potential Hazard, Moderate plausibility. "Product Information. Am J Obstet Gynecol 163 However, a much more significant risk has been reported with higher dosages, such as those used to treat prostate or metastatic breast cancer or those used in older formulations of birth control pills. (1989): 1000-4, Ewertz M "Oral contraceptives and breast cancer risk in Denmark." (1996): 255-7, Rosenberg L, Slone D, Shapiro S, Kaufman D, Stolley PD, Miettinen OS "Noncontraceptive estrogens and myocardial infarction in young women." Having successfully destroyed the supplies, Kassandra returned to Kyra. Applies to: Hepatic Tumor. Kyra wants you to destroy the supplies in the ruins on Delos Island. Ortho Novum 10/11 (ethinyl estradiol-norethindrone)." She found them at the Kynthos Ruins at the northern part of the island. Kyra: Don't exactly blend in, do you? For good measure, she also destroyed the weapon racks. 2. In Mykonos, Kyra seeks your help to weaken Podarkes’s grip on her compatriots. Spengler RF, Clarke EA, Woolever CA, Newman AM, Osborn RW "Exogenous estrogens and endometrial cancer: a case-control study and assessment of potential biases." Ogen (estropipate topical)" Pharmacia and Upjohn, Kalamazoo, MI. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: The most common adverse events were irregular uterine bleeding, nausea, breast tenderness, and headache. Estrogens and progestogens may cause retinal thrombosis. sertraline, fluoxetine, doxycycline, paroxetine, Zoloft, Prozac, NuvaRing, clindamycin topical, Sprintec, Xulane. Contraception 43 The use of exogenous estrogens may occasionally cause chloasma, especially in women with a history of chloasma gravidarum. Although not all of these side effects may occur, if they do occur they may need medical attention. Oral contraceptives and cervical cancer." Am J Epidemiol 124 J Adolesc Health 13 Arch Intern Med 137 Major Potential Hazard, Moderate plausibility. JAMA 261 Ann Intern Med 130 A Night to Remember. Acta Obstet Gynecol Scand Suppl 156 Civil Unrest. N Engl J Med 313 BMJ 299 Therapy with estrogens should be administered cautiously in patients with liver disease. Major Potential Hazard, High plausibility. Kaunitz AM "Long-acting injectable contraception with depot medroxyprogesterone acetate." Grin and Bear It. (1992): 1-46, Zondervan KT, Carpenter LM, Painter R, Vessey MP "Oral contraceptives and cervical cancer - further findings from the oxford family planning association contraceptive study." Pharmacia and Upjohn, Kalamazoo, MI. estrogen without concomitant progestin therapy) has been associated with a significant, dose-related risk of endometrial carcinoma. Applies to: Abnormal Uterine Bleeding.