 Of total iron in the human body,70% is present in haemoglobin & about 3%in myoglobin. Metals in Photosynthesis 7. Fe in bio systems 8. Cobalamines 6. Small molecule and biomolecular interactions enable not just the intake, uptake, and transport of essential elements, but also maintenance of the optimal level of the elements (homeostasis). Fixation of nitrogen Based on the relative concentrations in the biological systems, the metals are divided into: Bulk metals - Na, K, Mg & Ca Trace metals - Zn, Fe, Co, Ni, Cu, Mo, V etc., which are present in … General aspects of bioinorganic chemistry 3. Function of Zn 9. Hard ions: Na+, K, Mg2+, Ca 5. General aspects of bioinorganic chemistry 3. Cobalamines 6. The inorganic elements, especially the metals play an important role in biological systems. Hard ions: Na +, K , Mg2+, Ca2+ 5. Essential Elements follow a Dose-response curve.  Ferritin is major iron storage protein in mammals but is also found in plant … For metals, coordination chemistry … Coordination for uptake, transport and storage (Fe) 4. Bio-inorganic Chemistry Bioinorganic Chemistry is devoted to all aspects of “inorganic elements” (such as transition metals) as being vital for the growth and metabolism of living systems. ULTRATRACE ELEMENTS Needed at less than 1 ppm or 50 ppb Includes As, B, Si, Ni, V in humans Other elements include Br, Cd , F , Pb , Li, Sn Quite toxic at any concentration much above concentrations ultra trace level Essential Trace Elements  Iron  Iron is one of the metals found in greatest abundance in biological systems in the form of porphyrin complexes such as haemoglobin & myoglobin.  Most of the remaining iron is stored as ferritin. Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, Second Edition provides a detailed introduction to the role of inorganic elements in biology, taking a systematic element-by-element approach to the topic. Coordination for uptake, transport and storage (Fe) 4. Very important terms of coordination chemistry 2. 2. 1. Table 3.1 Approximate Elemental Composition of a Typical 70kg Human Bulk elements and mineral ions Phosphorus Potassium Chlorine Sulfur Sodium Magnesium Barium Molybdenum Boron Arsenic Cobalt Chromium Nickel Selenium Lithium Vanadium 680 g 250 g 21 mg 14 mg 14 mg —3 mg Oxygen Carbon Hydrogen Nitrogen Calcium 12.6 kg 6.6 kg Trace and ultra-trace elements Iron Silicon Zinc Rubidium Copper Strontium Bromine Tin …