For the qualitative HSAB theory the two properties are hardness and strength while for the quantitative ECW model the two properties are electrostatic and covalent. お客様のニーズに合ったより良いサービスを提供するために、当ウェブサイトではCookieを使用しています。個人情報の管理についてはプライバシーポリシー をご参照ください。当ウェブサイトを利用することにより、お客様はCookieの使用に同意することになります。, システムメンテナンスのお知らせ 2020年11月28日(土)午後6時~翌29日(日) 午後4時 : 当時間帯は当ウェブサイトがご利用いただけません。ご不便をおかけして申し訳ありませんがご理解のほどよろしくお願いいたします。, ・川口,尼崎倉庫の在庫は即日,その他の倉庫は2〜3営業日以内の出荷となります。 In the presence of strong acids, THF converts to a linear polymer called poly(tetramethylene ether) glycol (PTMEG), also known as polytetramethylene oxide (PTMO): This polymer is primarily used to make elastomeric polyurethane fibers like Spandex. In the presence of a solid acid catalyst, THF reacts with hydrogen sulfide to give tetrahydrothiophene.[27]. Manzer, L. E. "Tetrahydrofuran Complexes of Selected Early Transition Metals,", "New IUPAC Organic Nomenclature - Chemical Information BULLETIN", National Institute for Occupational Safety and Health, "Vapor Pressures, Densities, and PC-SAFT Parameters for 11 Bio-compounds", Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals, "NMR–MRI study of clathrate hydrate mechanisms", "Theoretical determination of molecular structure and conformation. Vapor LC50 Based on ATE data, the classification criteria are not met. こちらのフォーム よりお問い合わせください。, TCIの製品トピックスや新製品,製品パンフレット発行,展示会出展,キャンペーンなどをお知らせするメルマガです。ぜひ,ご登録ください。, ボラン - テトラヒドロフラン コンプレックス (8.5%テトラヒドロフラン溶液, 約0.9mol/L), テトラヒドロフランボラン (8.5%テトラヒドロフラン溶液, 約0.9mol/L). 0.9mol/L) (stabilized with Sodium Borohydride) Purity: For other uses, see, Except where otherwise noted, data are given for materials in their, Laurence, C. and Gal, J-F. Lewis Basicity and Affinity Scales, Data and Measurement, (Wiley 2010) pp 50-51 IBSN 978-0-470-74957-9. About 200,000 tonnes of tetrahydrofuran are produced annually. ATE > … It can be used to liquefy old PVC cement and is often used industrially to degrease metal parts. However, the molecular species BH 3 is a very strong Lewis acid. [22][23][24] It has been shown that to define the order of Lewis base strength at least two properties must be considered. THF readily dissolves latex and is typically handled with nitrile or neoprene rubber gloves. THF is used as a solvent in 3D printing when using PLA plastics. THF is a weak Lewis base that forms molecular complexes with many transition metal halides. There are seven possible structures, namely,[28], "THF" redirects here. [9] The most widely used industrial process involves the acid-catalyzed dehydration of 1,4-butanediol. [8] Being polar and having a wide liquid range, THF is a versatile solvent. ATE > 2000 mg/kg. It has a greater elution strength than methanol or acetonitrile, but is less commonly used than these solvents. THF is a relatively nontoxic solvent, with the median lethal dose (LD50) comparable to that for acetone. It is a popular solvent for hydroboration reactions and for organometallic compounds such as organolithium and Grignard reagents. Drago, R. S. Applications of Electrostatic-Covalent Models in Chemistry, Surfside: Gainesville, FL, 1994. [10] A third major industrial route entails hydroformylation of allyl alcohol followed by hydrogenation to 1,4-butanediol. THF is a Lewis base that bonds to a variety of Lewis acids such as I2, phenols, triethylaluminum and bis(hexafloroacetylacetonato)copper(II). Tetrahydrofuran Borane (8.5% in Tetrahydrofuran. It is more basic than diethyl ether[18] and forms stronger complexes with Li+, Mg2+, and boranes. Borane - Tetrahydrofuran Complex (8.5% in Tetrahydrofuran, ca. THF concentrations in adipose tissue and kidneys were 1.3-1.4 times higher than in blood; levels in liver, brain, spleen, and muscle were similar to blood. 0.9mol/L) (stabilized with Sodium Borohydride) The biological half-life in blood was 5 hr. For example, it can be used to dissolve polymers prior to determining their molecular mass using gel permeation chromatography. [19] Thus, while diethyl ether remains the solvent of choice for some reactions (e.g., Grignard reactions), THF fills that role in many others, where strong coordination is desirable and the precise properties of ethereal solvents such as these (alone and in mixtures and at various temperatures) allows fine-tuning modern chemical reactions. は各々異なります。 Reflecting its remarkable solvent properties, it penetrates the skin, causing rapid dehydration. The method is similar to the production of diethyl ether from ethanol. ・納期に関するご質問につきましては営業部までお問い合わせください。 [本社営業部]Tel: 03-3668-0489 [大阪営業部]Tel: 06-6228-1155 [17] Aqueous THF augments the hydrolysis of glycans from biomass and dissolves the majority of biomass lignin making it a suitable solvent for biomass pretreatment. Tetrahydrofuran (THF), or oxolane, is an organic compound with the formula (CH 2) 4 O. [8] It is an aprotic solvent with a dielectric constant of 7.6. CAS RN: 14044-65-6 | 製品コード: T2346. One danger posed by THF follows from its tendency to form the highly explosive peroxides tetrahydrofuran hydroperoxide on storage in air. The puckering of oxolanes", "2-Methyltetrahydrofuran, An alternative to Tetrahydrofuran and Dichloromethane", https://en.wikipedia.org/w/index.php?title=Tetrahydrofuran&oldid=976864275, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, Monoxolane, the root of the group, synonymous with, This page was last edited on 5 September 2020, at 14:29. ・キロ~トンスケールの量をご入用の場合は,「大量製造見積依頼」ボタンをクリックし専用フォームでお問い合わせください。一部の製品についてはご希望に添えない場合もございますので,予めご了承ください。 It is a moderately polar solvent and can dissolve a wide range of nonpolar and polar chemical compounds. Typical complexes are of the stoichiometry MCl3(THF)3. It is mainly used as a precursor to polymers. よりお問い合わせください。, • 製品コード,ロット番号が正しいにもかかわらず書類を閲覧することができない場合は,  Trihydridoboron, also known as borane or borine, is an unstable and highly reactive molecule with the chemical formula BH 3.The preparation of borane carbonyl, BH 3 (CO), played an important role in exploring the chemistry of boranes, as it indicated the likely existence of the borane molecule. THF has been explored as a miscible co-solvent in aqueous solution to aid in the liquefaction and delignification of plant lignocellulosic biomass for production of renewable platform chemicals and sugars as potential precursors to biofuels.